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Publication 52 specifically addresses Hazardous, Restricted, and Perishable Mail, providing comprehensive guidelines and regulations for the mailing of these specific types of items. This includes instructions on how to properly package, label, and handle materials that may pose safety risks, are limited in transportation, or require special consideration due to their nature (like perishable goods).

Understanding the requirements outlined in Publication 52 is crucial for individuals and businesses engaged in shipping items that fall under these categories. The guidance ensures compliance with postal regulations, helps prevent accidents, and ensures safe delivery of sensitive or potentially dangerous items. This publication is an essential resource for anyone involved in mailing that includes hazardous materials, ensuring they understand the specific regulations that exist to protect carriers and recipients alike.